A carrier-free multiplexed gene editing system applicable for suspension cells
نویسندگان
چکیده
منابع مشابه
Stereospecificity of the glucose carrier in sugar beet suspension cells.
The stereospecificity of the binding site on the glucose carrier system in sugar beet suspension culture cells was determined using a series of aldo and keto hexose sugars and sugar alcohols. Specificity was determined as competition with [(14)C]glucose transport and glucose/proton symport.The binding site of the glucose carrier system was specific for the stereo orientation of the three equato...
متن کاملOptimal Roll Center Height of Front McPherson Suspension System for a Conceptual Class A Vehicle
In this paper, the effects of roll center height of McPherson suspension mechanism on dynamic behaviour of a vehicle are first studied, and then the optimum location of roll center of this suspension system is determined for a conceptual Class A vehicle. ADAMS/Car software was used for the analysis of vehicle dynamic behaviour in different positions of suspension roll center. Next, optimization...
متن کاملThe new genomic editing system (CRISPR)
Over the past decades, progression in genetic element manipulation, and consequently, the treatment of diseases has been remarkable. It is worth noting that these genetic manipulations perform at different levels, including DNA and RNA. The earlier genomic editing techniques, including MN, ZFN , TALEN , performing their functions by creating double-stranded breaks (DSBs), and after breakage, th...
متن کاملSRL-coated PAMAM dendrimer nano-carrier for targeted gene delivery to the glioma cells and competitive inhibition by lactoferrin
Glioma, as a primary tumor of central nervous system, is the main cause of death in patients with brain cancer. Therefore, development of an efficient strategy for treatment of glioma is worthy. The aim of the current study was to develop a SRL peptide-coated dendrimer as a novel dual gene delivery system for targeting the LRP receptor, an up-regulated gene in both BBB and glioma cells. To perf...
متن کاملA Polynomial Kernel for Diamond-Free Editing
An H-free editing problem asks whether we can edit at most k edges to make a graph contain no induced copy of the fixed graph H. We obtain a polynomial kernel for this problem when H is a diamond. The incompressibility dichotomy for H being a 3-connected graph [4] and the classical complexity dichotomy [1] suggest that except for H being a complete/empty graph, Hfree editing problems admit poly...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biomaterials
سال: 2019
ISSN: 0142-9612
DOI: 10.1016/j.biomaterials.2019.119298